The differences in the frequency of KRAS mutations could be related to racial features, as described by Staudacher et al. in a meta-analysis of 4648 CRC patients, where non-Hispanic White people exhibited fewer mutations in KRAS codon 12 or codon 13 than African Americans (OR 0.640; 95% CI: 0.5342–0.7666; p = 0.0001) [40]. The gene discussed is KRAS; the disease is colorectal carcinoma.