A meta-analysis of 70 studies evaluating molecular analysis in the diagnosis and prediction of the prognosis of STS demonstrated that FISH for MDM2 amplification, RT-PCR for SYT-SSX fusion, and CTNNB1 mutation were useful for WDLPS/DDLPS, synovial sarcoma, and desmoid tumors, respectively [33]. The gene discussed is CTNNB1; the disease is synovial sarcoma.