NF1 and paraganglioma: Indeed, most GISTs are sporadic, while about 5% of cases occur in patients with genetic syndromes such as Carney–Stratakis syndrome (dyad), Carney triad syndrome (SDH-deficient GIST, pulmonary chondroma, paraganglioma), familiar Neurofibromatosis type 1 (NF-1) (multifocal, mainly small bowel SDH-deficient GISTs), and primary familial GIST syndrome [35,36].