LGALS3 and Myocardial fibrosis: Some studies have shown that circulating biomarkers of myocardial fibrosis, such as galectin-3 (Gal-3), C-terminal propeptide of type I procollagen (PICP), and N-terminal propeptide of type III procollagen (PIIINP), may provide additional information about the pre-fibrotic state of the myocardium because they reflect collagen turnover [18,19].