The total number of study participants was 148, of whom we included 44 patients with nodular goiter (one patient had two analyzed thyroid nodules) that have fulfilled study inclusion criteria and in which we performed 99mTc-MIBI semi-quantitative thyroid scans (visual image results, visual pattern and 99mTc-MIBI wash-out), and 70 patients were addressed for prospective BRAF collection from FNAC. The gene discussed is BRAF; the disease is thyroid nodule.