To determine if the activation of NK cells from leukemia patients is dependent on their NK receptors (NCR), we evaluated the expression of NKG2D and NKp44 receptors in the different NK subpopulations by culturing PBMC for 24 h with Poly I:C, Imiquimod, R848 or ODN2006 (Figure 6). Here, KLRK1 is linked to leukemia.