No significant differences in the expression of Aβ, Tau, or pTauser199 or the pTauser199/Tau ratio were found in the mPFC in ICV-STZ rats, suggesting that AD-related pathological changes were not predominant in the mPFC on d 7 after ICV-STZ treatment (Figure 1G–K). The gene discussed is MAPT; the disease is Alzheimer disease.