Five of the 14 diabetes-related genes, FOXA1, KIF22, PAK4, MTA3, and FGFR3, were specifically highly expressed in only the ER+/PR+ and ER+/PR− subtypes but not ER−/PR+ and ER−/PR− through an analysis using 4032 patient tissue samples from Breast Cancer Gene Expression Miner v4.5 (Figure 2). This evidence concerns the gene PAK4 and breast cancer.