CRC-derived exosomes harbor a diverse array of biomolecules, including proteins (e.g., TGFβ, VEGFA, αvβ5 integrin, PAD4, WNT4), RNA (e.g., miR-25-3p, miR-21, miR-27a, miR-10b, miR-2149-5p, miR-6737-5p, miR-6819-5p), and DNA. The gene discussed is TGFB1; the disease is colorectal carcinoma.