In another study, exosomes isolated from Fusobacterium nucleatum (Fn) were used to infect CRC cells, and it was found that Fn infection transported miR-1246/92b-3p/27a-3p and CXCL16/RhoA/IL-8 into non-infected cells, thereby enhancing the cell migration ability in vitro and promoting tumor metastasis in vivo. Here, CXCL16 is linked to neoplasm.