The importance of miR-584-5p target genes in the progression of NSCLC tumors is supported by several works; for instance, higher levels of YKT6 [60] (a protein involved in the production and release of exosome) and of MMP-14 (an important Matrix metalloproteinase) [61] are correlated with the shorter overall survival of these patients. This evidence concerns the gene YKT6 and non-small cell lung carcinoma.