In all of our cultured pancreatic cancer cell lines (human—PANC1 and BxPC3, mouse—LTPA and Pan02), GH and GHR protein expression is confirmed by western blot (Figure 1D), while GHR protein expression is confirmed by immunocytochemistry as well (Figure 1E), indicating an autocrine loop. The gene discussed is GHR; the disease is pancreatic neoplasm.