Querying one of the largest pancreatic cancer patient transcriptome profiles, which includes 1640 samples combining 16 available GEO datasets [24], we observed that increased GHR expression significantly and negatively correlates with DFS [hazard ratio (HR) = 2.16, p = 0.0003] and survival (9 vs. 17 months) in human PDAC patients (Figure 1A and Figure S3). The gene discussed is GHR; the disease is familial pancreatic carcinoma.