TNF and relapsing-remitting multiple sclerosis: In patients with newly diagnosed RRMS, IL-15 levels in CSF correlated negatively with both the number of T2 lesions in C spine MRI and the number of Gd(+) lesions in C spine MRI, while TNFα, PDGF-bb, and FGF basic in CSF correlated positively with the number of T2 lesions in C spine MRI (Table 7).