In male MMP-3 KO stroke mice, the mean infarct volume was 18.27 ± 1.56% (**** p < 0.0001 vs. sham), which was significantly smaller than in the male WT MCAO/R group (####p < 0.0001 vs. MCAO/R WT) (Figure 1A). Here, MMP3 is linked to Stroke.