Key inflammation-associated genes downregulated upon MMP-3 KO in female stroke brains included Tnfsf9, Il6, Tnfrsf9, Tnfrsf1b, Ccrl2, Cxcl5, Ccl7, Ccr7, Fos, Tnf, Jun, Tnfrsf1a, Icam2, Pecam1, Il1rn, Il4ra, Mmp9, Cxcl1, Ccr1, and Ccl11 (Figure 4E, Figure 5A–C and Figure A3C). The gene discussed is TNFRSF9; the disease is stroke disorder.