BRD2 and obesity due to melanocortin 4 receptor deficiency: Some also hypothesized that follicle-stimulating hormone (FSH) may also play a role in menopause-induced obesity, as blocking FSH interaction with its receptor by an administration of FSH antibodies protected both male and female mice against HFD-induced obesity by inducing the browning of WAT, thermogenesis, and increasing energy expenditure [43].