The majority of MCL cases (>95%) feature the abnormal chromosomal translocation t(11;14)(q13;q32)(IgH/CCND1), leading to constitutive cyclin D1 (CCND1) overexpression inducing cell-cycle deregulation, along with deregulation of DNA damage and repair mechanisms and transcriptional alterations [3,4,5]. Here, CCND1 is linked to mantle cell lymphoma.