In this context, among the markers that can contribute to portraying this pathology and its associated complications are blood glucose levels (an increased glycemia can be associated with obesity), the insulin/insulin-like growth factor ratio (INS/IGF-1 outside optimal parameters can indicate insulin resistance, often associated with obesity, the lipid profile (unbalanced values of LDL, HDL, and triglycerides are often found in obesity and associated pathologies), and the C-reactive protein ([CRP] as a marker of low-grade chronic inflammation that occurs in obesity). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.