Hunter et al. [107] observed a significant reduction in mRNA levels of glutathione S-transferase isoforms mu1 (GSTM1) and mu5 (GSTM5) in AMD patients compared to age-matched controls, particularly in the retinal pigment epithelium (RPE)/choroid and neurosensory retina. The gene discussed is GSTM5; the disease is age-related macular degeneration.