Since IL-6 stimulation induces CYP19A1 steady-state mRNA levels in endometrial cancer stromal cells using the dermal-specific promoter I.4 [18], we examined if CYP19A1 steady-state mRNA levels increase in dermal fibroblasts in response to stimulation of E2 and/or recombinant IL-6 (IL-6) and its soluble receptor (sIL-6R). The gene discussed is CYP19A1; the disease is endometrial cancer.