CXCL8 and Sepsis: Figure 1A illustrates longitudinal IL-8 levels in burns patients and HC, with IL-8 levels significantly higher at days 3 and 5 post-burn (p < 0.05). Figure 1B shows the comparison of IL-8 levels between burns patients who did or did not develop sepsis. IL-8 concentrations were significantly higher at day 5 post-burn in patients with sepsis (p < 0.001). A comparison of IL-8 levels between patients with and without sepsis and HC found IL-8 was significantly increased in patients who developed sepsis compared to HC at days 3, 5, 7 (p < 0.001), 10 (p < 0.05) 12 and 14 (p < 0.01) (Figure 1C,D).