The total number of immune cells in the tumor was further compared between the two groups, and it was found that the proportion of immune cells in the total cells in tumor tissue significantly increased in the SINV-GM-CSF group compared with the control group (Figure 4B); in addition, the number of Natural killer cells (NK cells), Dendritic cells (DCs), B cells, and neutrophils rose (Figure 4C). This evidence concerns the gene CSF2 and neoplasm.