ACAN and dentin dysplasia: Interestingly, studies conducted using palmar fascia from the lesion of DD and from clinically unaffected by Dupuytren as well as from normal forehand fascia, using different methodological approaches showed that the immunohistochemical expression of decorin was high in DD, whereas versican was highly expressed in the normal fascia, with no differences for aggrecan, besides increase in collagen content.