To validate the revealed association of rs3761548 variant and FOXP3 methylation status with PTC, we performed genotypic analysis of rs5953283 PPP1R3F polymorphism, previously related to asthma [19], in order to examine if this variant and gene, due to linkage disequilibrium (LD), misled to the revealed FOXP3 association with PTC predisposition. The gene discussed is FOXP3; the disease is asthma.