Tanshinone IIA, which is mainly derived from Salvia miltiorrhiza Bunge (Labiatae), downregulates transforming growth factor beta 1 (TGFβ1) in addition to targeting TXNIP, thereby alleviating renal tubular epithelial cell inflammation and sepsis induced by hyperglycemia, a process in which the NF-κB pathway is involved [99]. The gene discussed is NFKB1; the disease is Hyperglycemia.