Notably, during infection, the synthesis levels of superoxide (O2•−)-, hydroxyl (HO•)-, peroxyl (RO•−2)-, and hydroperoxyl (HO•2)-derived ROS, nitric oxide (NO)-derived RNS, the transcription of the inducible NO synthase (iNOS) gene, and the phosphorylation of STAT-1 significantly increase as they are beneficial for host defense mechanisms and pathogen clearance [65,66,67]. This evidence concerns the gene NOS2 and infection.