Myofibroblasts contribute to airway remodeling in the long-term complication of asthma depending on the inflammatory microenvironment [44]; one of the principal products of these pathological cells are αSMA fibers; TGF-β1 induces transient upregulation of COL1A1 and αSMA important fibrosis markers [45]. Here, ACTA1 is linked to asthma.