Figure 5 illustrates the markers expression of the fibrosis process due to asthma, showing an over-expression of the collagen1a1 and αSMA corroborated fibrosis and remodeling with clusters of collagen fibers in the bronchial epithelium by Masson’s trichrome stain where collagen is stained blue, and smooth muscle tissue is stained red. The gene discussed is ACTA1; the disease is asthma.