Also, a clinical trial (NCT03312530) evaluating the safety and the efficacy of cobimetinib showed promising results when this MEK inhibitor was administrated alone or in combination with venetoclax (BCL-2 inhibitor) with or without atezolizumab (PD-L1 inhibitor) in t(11;14) MM patients [106,107]. This evidence concerns the gene MAP2K7 and Miyoshi myopathy.