WRB (tryptophan-rich basic protein, also known as GET1, guided entry of tail-anchored proteins factor 1, at 21q22.2) and TSPAN10 (tetraspanin 10 at 17q25.3), which were detected as a susceptibility gene for esotropia in the U.S.A. [33] and for self-reported strabismus of unknown entity in the U.K. [34], respectively, were also not replicated by the present GWAS (see regional plots in Supplementary Figure S2). The gene discussed is TSPAN10; the disease is Esotropia.