Moreover, the basis for the inclusion of TLR2 and TLR4 genes in our genetic association study is the results of Wang and coworkers’ study: both genes are present on the prioritized list of dental caries candidate genes provided by ENDAVOUR, created taking into consideration the magnitude of evidence related to dental caries; TLR2 gene was ranked 158, whereas TLR4 gene was ranked 376 out of 960 candidate genes [31]. The gene discussed is TLR4; the disease is dental caries.