The analysis of the association between the TLR2 and TLR4 SNPs and caries susceptibility, assessed using dominant and recessive genetic models, revealed no statistically significant association between TLR2 (rs5743708) and TLR4 (rs4986790 and rs4986791) gene polymorphisms and susceptibility to dental caries (Table 1 and Table 2). The gene discussed is TLR4; the disease is dental caries.