NASH–HCC transition: In an MYC-ON MCD NAFLD mouse model, Chi Ma et al. showed that the disruption of mitochondrial function by linoleic acid from NAFLD liver caused oxidative damage and mediated the selective loss of intrahepatic CD4+T lymphocytes but not of CD8+T lymphocytes. The gene discussed is MYC; the disease is metabolic dysfunction-associated steatotic liver disease.