Figure 3A shows a representative flow cytometric analysis for the tetramer detection of CTLs without culture and for CTL functions after antigenic stimulation. The maximum CTL responses, including IFN-γ production, MIP-1β production, and degranulation measured by CD107a expression, were not different between HLA-A*02- and HLA-A*24-positive HAM/TSP patients (Figure 3B). The gene discussed is HLA-A; the disease is tropical spastic paraparesis.