Utilizing univariate Cox regression analysis, we identified seven TAS2Rs genes associated with prognosis in colon cancer patients, including TAS2R4, TAS2R5, TAS2R14, TAS2R19, TAS2R20, TAS2R31, and TAS2R38 (Supplementary Figure S2). The gene discussed is TAS2R4; the disease is malignant colon neoplasm.