Consistent with previous research findings, CBLL1, FTO, LRPPRL, METTL3, RBM15, YTHDF1, and ZC3H13 are expressed at high levels in colon cancer tissues, while their expression levels are low in normal colon tissues; ALKBH5 is underexpressed in colon cancer tissues but overexpressed in normal colon tissues [37]. The gene discussed is YTHDF1; the disease is malignant colon neoplasm.