Breast cancer, the most common cancer in women worldwide, has diverse types based on hormone and human epithelial growth factor receptor 2 (HER2) status: luminal A/B, HER2-positive, and triple-negative (TNBC). Zinc imbalance is linked to breast cancer, with low serum zinc but high zinc in cancer tissues. Zinc plays a crucial role in cancer progression, affecting cell transformation and tumor aggressiveness by influencing zinc transporters. Here, ERBB2 is linked to breast cancer.