Through the inhibition of mTOR signaling and autophagy activation, P. notoginseng saponins (R1, Rg1, and Rb1), at the concentration of 0.1–1 μg/mL, exerted neuroprotective effects in PC12 cells exposed to 20 μM β-amyloid (Aβ), an in vitro model of Alzheimer’s disease (AD) [64]. The gene discussed is MTOR; the disease is Alzheimer disease.