After Akpinar et al. found high levels of pigment epithelium-derived factor (PEDF) in subjects with CD and analyzed their effects on angiogenesis, Dikker et al. correlated these results with other studies that investigated the levels of PEDF in subjects with hepatic steatosis, arguing that both diseases occur on a common inflammatory background [57,58], and suggested that patients with CD and high levels of PEDF need further investigation for the presence of steatosis and vice versa [58]. The gene discussed is SERPINF1; the disease is fatty liver disease.