Similarly, another clinical study also observed that the expression of various pro-inflammatory factors, such as CRP, IL-6 and TNF-α, was significantly reduced in the elderly after eating defatted BC, and the results of non-targeted metabolomic analysis showed that BC may cause changes in glycerophospholipid metabolism, cysteine, and methionine metabolism pathways, which effectively regulated the immune function and inflammatory status of the elderly. This evidence concerns the gene IL6 and breast cancer.