CRP and diabetes mellitus: After performing binary logistic regression, the following variables were identified to be independently associated with CNS involvement in severe COVID-19 patients: female sex (p = 0.04, OR 3.67, 95%CI 1.05–12.85), diabetes mellitus (p = 0.008, OR 5.088, 95%CI 1.519–17.04), lymphocyte count (0.04, OR 0.23, 95%CI 0.05–0.97), platelets count (p = 0.001, OR 0.98, 95%CI 0.98–0.99), CRP value (p = 0.04, OR 1.007, 95%CI 1.000–1.015), and CK value (p = 0.004, OR 1.003, 95%CI 1.001–1.005).