The primary features for predicting sustained response are listed in descending order of importance, including the DAS28-ESR Score, HAQ Score, SDAI Score, VAS pain, age, VAS for patients, BMI, TJC28, RF, CDAI Score, DAS28-CRP score, CRP level, ESR level, VAS for physicians, asthma status, csDMARD usage, RF and gender. This evidence concerns the gene ESR1 and asthma.