The causative genes of PFBC include SLC20A2 [2], PDGFB [3], PDGFRB [4] and XPR1 [5] with an autosomal dominant inheritance, and MYORG [6], JAM2 [7], CMPK2 [8] and NAA60 [9] with an autosomal recessive inheritance, but about 50% of patients do not carry mutations in known genes, suggesting additional, still unknown genetic contributors. This evidence concerns the gene PDGFRB and bilateral striopallidodentate calcinosis.