Pericardiac effusion with or without signs of pericarditis was reported mostly during the acute COVID-19 phase, although there is an increasing number of authors describing pericardial involvement as a delayed complication of SARS-CoV-2 infection, probably caused by the release of proinflammatory cytokines (interleukin [IL]-1β, IL-6, IL-8, IL-2 and tumor necrosis factor-α) [4,29]. This evidence concerns the gene CXCL8 and COVID-19.