Secondly, the systemic inflammatory response syndrome (SIRS) induced by COVID-19 can lead to a cytokine storm, characterized by the release of large quantities of pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-alpha (TNF-α). Here, IL6 is linked to systemic inflammatory response syndrome.