It is now known that mutations in Kv genes (KCNQ1–5) are related to several disorders like long-QT syndromes (KCNQ1) and a range of neuropsychiatric disorders (KCNQ2–5), ranging from some types of neonatal epilepsy (NEE) and epileptic encephalopathies (DEEs) up to developmental disorders [20,21,22]. Here, KCNQ1 is linked to Epileptic encephalopathy.