TBK1 and cancer: The phosphorylated TBK1 and IKK stimulate the transcription factors interferon nuclear factor κB (NF-κB) and interferon regulatory factor 3 (IRF3), eliciting the expression of proinflammatory cytokines such as interleukin 6 (IL-6) and type I interferons (IFN-I) to kill cancer cells [7,8].