However, in one study conducted for over one year, examining the changes in prolactin levels among first-episode schizophrenia patients treated with one of four atypical antipsychotics (olanzapine, quetiapine, amisulpride, ziprasidone), it was observed that the administration of these medications did not lead to a significant increase in prolactin levels in either men or women [19]. The gene discussed is PRL; the disease is schizophrenia.