Furthermore, histopathology revealed a significant accumulation of lipids in the liver tissues of mice that were fed a high-fat diet (HFD), and serum AST, ALT, TC, TG, and LDL-C decreased significantly after CLSPAJ supplementation, indicating that CLSPAJ was effective in alleviating liver injury caused by a HFD and the potential anti-obesity ability [21]. Here, GPT is linked to obesity due to melanocortin 4 receptor deficiency.