Our analysis of the DEGs between Fresh-ET vs. NC and FET vs. NC revealed that they were largely enriched onto the same pathways, such as cell cycle, progesterone-mediated oocyte maturation, motor proteins, p53 signaling pathway, oocyte meiosis, cellular senescence, ECM-receptor interaction, and Cushing syndrome. The gene discussed is TP53; the disease is Cushing syndrome due to macronodular adrenal hyperplasia.