Furthermore, a significant effect was noted for the interaction of time and treatment regarding right ovarian volume (p = 0.002), left ovarian volume (p = 0.010), endometrial thickness (p = 0.002), Testosterone (p = 0.001), hirsutism severity score (p < 0.001), and LH (p < 0.001). The gene discussed is PLOD1; the disease is Hirsutism.