IL1B and nasopharyngeal carcinoma: However, the mechanisms underlying IVDD and NPC degeneration remain unclear.<h4>Methods</h4>We used interleukin (IL)-1β stimulation to establish an NPC-degenerated IVDD model and investigated whether human urine-derived stem cell (USC) exosomes could prevent IL-1β-induced NPC degeneration using western blotting, quantitative real-time polymerase chain reaction, flow cytometry, and transcriptome sequencing techniques.<h4>Results</h4>We successfully extracted and identified USCs and exosomes from human urine.