CSF3 and Decreased total neutrophil count: Salvage G-CSF occured in 18 patients (34.6%) for 21 cycles (11.5%), including 9 cycles with grade 3–4 neutropenia within 14 days of administration PEG-rhG-CSF during CCRT, 9 cycles with grade 2 neutropenia after 14 days of administration during CCRT, 2 cycles with FN, and 1 cycle with grade 4 neutropenia during induction chemotherapy.