ADAR and amyotrophic lateral sclerosis: Our gene expression analysis (Additional file 6) did not reveal a statistically significant difference in ADAR1 or ADAR2 mRNA levels between control and ALS-Ox cases (Unpaired, two-tailed t-test p values 0.4548 and 0.0624 respectively), even though we observed a trend towards downregulation in the case of ADAR2.