AR and neoplasm: We calculated the CCP scores, AR activities, and CRPCsig51 scores for tumor samples in the TCGA-PRAD, DKFZ-PRAD, and Meta-Cohort and found that higher RAECsig scores were significantly correlated with both CCP and CRPCsig51 scores while weakly correlated with negative androgen activities (Fig. 6a–c and Fig. S9A, B).