We also compared lymphocyte chemotaxis in the context of AAV6-CXCL9 transduced tumor cells versus AAV6-CXCL9 transduced astrocytes, and found that lymphocytes were evenly distributed in both the astrocyte field and tumor field (Supplementary Fig. S5a), even though increased levels of CXCL9 secretion were detected in the tumor field (Supplementary Fig. S5b). This evidence concerns the gene CXCL9 and neoplasm.